Deepak Solanki, PhD Scholar
Department of Pharmacology
Institute of Pharmacy, Nirma University.
Research Interests:
I am a dedicated PhD scholar focusing on cutting-edge research in the field of oncology, with a particular interest in breast cancer therapeutics. My current research investigates the antineoplastic properties of ATP synthase inhibitors, in breast cancer models. My work spans both in vitro studies with MDA-MB-231 cell lines and in vivo xenograft models with the goal of exploring potential synergies with existing chemotherapeutic agents and targeting tumor growth and metastasis. I am also keenly interested in drug delivery systems, including nanotherapeutics.
Current Research Project:
My PhD project, titled "Preclinical Evaluation of ATP Synthase Inhibitor’s Antineoplastic Properties in Breast Cancer Models," focuses on assessing the therapeutic potential of ATP synthase inhibitors for breast cancer treatment. By studying key molecular pathways, including mitochondrial dysfunction, apoptosis, and tumor microenvironment modulation, I aim to contribute to novel treatment strategies that may improve outcomes for breast cancer patients.
Professional Experience and Expertise:
• Formulation development of nanotherapeutics for brain-targeting in Alzheimer's disease treatment.
• Expertise in designing and conducting in vitro cell line studies and in vivo xenograft models.
• Skilled in evaluating biochemical markers related to cancer cell proliferation, apoptosis, angiogenesis, and inflammation.
• Experience in systematic reviews and meta-analyses on neurodegenerative diseases.
Academic Background:
I hold a Master’s degree in Pharmacology from JSS college of pharmacy. My background includes significant work in the intersection of oncology and neurodegenerative diseases, focusing on the development of targeted therapeutic strategies.
Publications:
1. Kaustav Nag, Deepak Solanki, Muthukumar Serva Peddha, Seema Mehdi, Rajan Logesh, Tamsheel Fatima Roohi, Nabeel Kinattingal, Faiyaz Shakeel, Effect of cyclodextrin-complexed lyophilized nanosuspension of Nigella sa
